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ZUVIPLAT solution should be used intravenously only and should be administered by i.v dose every 3-4 week. An alternative regimen is 15-20 mg per sq. i.v daily for 5 days every 3-4 week In clinical use of ZUVIPLAT injection, take the following measure for reducing the nephrotoxicity of the drug: Administer 1000-2000 ml. of an adequate fluid deficit replacement over 4 hours or more prior to the administration of ZUVIPLAT injection. Administer ZUVIPLAT injection as a mixture with 500-1000 ml of physiological saline or a dextrose –saline solution by intravenous drip over 2 hours or more. When it take the intravenous drip over 2 hours or more. When it take the intravenous drip of