Polysorbate 80 is regarded as a safe chemical in skincare and is used as an emulsifier to combine oil and water, it is also additive used in processed food products for its emulsifying properties (ability to prevent fats from separating out). Commercially produced frozen desserts, shortenings, baking mixes and icings, and canned vegetables are some of the foods that may contain polysorbate 80.Polysorbate 80 is a synthetic nonionic surfactant used as an excipient in drug formulation. Various products formulated with polysorbate 80 are used in the oncology setting for chemotherapy, supportive care, or prevention, including docetaxel, epoetin/darbepoetin, and fosaprepitant.