It is difficult to overestimate the importance of healthy oral microflora for the body. It is in this environment that the primary process of food digestion takes place, and, therefore, the absorption of vitamins and nutrients. Normal microflora is essential for the proper functioning of the immune system and the body's defense against fungal, bacterial and viral infections. With the uncontrolled reproduction of pathogenic microflora, dysbacteriosis of the oral cavity occurs, which provokes damage to tooth enamel and gums. With probiotics, they restore and control the acid-base balance and immunity of the oral cavity, relieve inflammation, bleeding of the gums, and suppress the growth of pathogens. Tourmaline nano particles with the help of released ions and infrared radiation enhance the effect of the probiotic.