Pizotifen has an appetite-stimulating action suitable for increasing body weight in underweight anorectic patients. The compound is well tolerated, permitting treatment of anorexia both in children and adults.
Owing to its inhibitory effect on biogenic amines, pizotifen is also used for the prophylactic (interval) treatment of migraine.
The B-complex vitamins B1, B2, B6 and nicotinamide prevent deficiencies of these vitamins often associated with inadequate food intake. Such a need may also arise from antibiotic or other drug therapy with vitamin utilization.