Appendicitis is an inflammation of the appendix, a 3 1/2-inch-long tube of tissue that extends from the large intestine. ... Left untreated, an inflamed appendix will eventually burst, or perforate, spilling infectious materials into the abdominal cavity
What Causes Appendicitis?
Appendicitis occurs when the appendix becomes blocked, often by stool, a foreign body, or cancer. Blockage may also occur from infection, since the appendix swells in response to any infection in the body